Core-2 O-glycans are required for galectin-3 interaction with synovial lubricin

PubMed Entry

Peak Intensity
209.04 0.3
209.61 0.0
210.12 0.0
210.69 0.0
211.2 0.0
211.77 0.0
212.28 0.0
212.83 0.0
213.36 0.0
215.77 0.2
216.25 0.3
216.79 0.0
217.35 0.0
217.87 0.0
218.42 0.0
218.95 0.0
219.59 0.4

Annotations:

CY
219.93 0.5

Annotations:

CY
221.24 0.9

Annotations:

^{2,4}A_{GalNAc} ^{2,4}A_{GlcNAc}
222.08 0.5

Annotations:

YY
222.66 0.0
223.14 0.0
223.74 0.0
224.21 0.0
224.83 0.0
225.2 0.4
225.77 0.0
226.29 0.0
226.85 0.0
227.59 0.2
228.01 0.5
228.55 0.0
229.11 0.0
229.63 0.0
230.19 0.0
230.71 0.0
231.27 0.0
232.06 0.3
232.62 0.0
233.01 1.0
233.57 0.0
233.96 0.5
234.52 0.0
235.07 1.1

Annotations:

^{3,5}A_{GlcNAc}
235.65 0.0
236.21 0.0
236.73 0.0
237.29 0.0
237.81 0.0
238.36 0.0
238.89 0.0
239.43 0.0
239.91 0.2
240.46 0.0
241.02 0.0
241.54 0.0
242.1 0.0
242.62 0.0
243.16 0.0
243.83 2.5

Annotations:

^{0,4}A_{GalNAc}Z
244.4 0.0

Annotations:

^{0,4}A_{GalNAc}Z
244.98 0.0
245.47 0.0
245.88 1.3
246.27 1.0
246.86 0.3
247.21 0.0
247.44 0.0
247.95 0.0
248.5 0.0
249.03 0.0
249.36 0.9
249.94 0.0
250.45 0.0
250.99 0.0

Annotations:

^{0,3}A_{GlcNAc}
251.53 0.0

Annotations:

^{0,3}A_{GlcNAc}
252.06 0.0
252.61 0.0
253.13 0.0
253.69 0.0
254.21 0.0
257.82 0.6

Annotations:

^{3,5}A_{GalNAc}Z
258.37 0.0

Annotations:

^{3,5}A_{GalNAc}Z
258.91 0.0
259.45 0.0
259.98 0.0
260.53 0.0
261.05 0.0
261.61 0.0

Annotations:

^{0,4}A_{GalNAc}Y ^{1,3}A_{GalNAc}
262.6 10.9
263.1 3.5
263.68 0.0
264.2 0.0
265.0 0.3

Annotations:

^{2,5}A_{GlcNAc}
265.54 0.0

Annotations:

^{2,5}A_{GlcNAc}
265.84 0.0
266.1 0.0
266.62 0.0
266.92 0.0
267.19 0.0
267.7 0.0
268.26 0.0
268.78 0.0
269.32 0.0
269.86 0.0
274.1 0.3

Annotations:

^{0,3}A_{GalNAc}Z
274.68 0.0
275.19 0.0
275.96 0.9

Annotations:

^{3,5}A_{GalNAc}Y
276.53 0.0

Annotations:

^{3,5}A_{GalNAc}Y
277.07 0.0
277.61 0.0
278.14 0.0
278.77 0.5
279.35 0.0
280.02 2.7
280.51 0.7
281.03 0.7

Annotations:

^{0,2}A_{GlcNAc}
281.63 0.1
282.19 0.0
282.72 0.0
283.27 0.0
283.79 0.0
284.35 0.0
284.87 0.0
285.39 0.3
285.85 0.2
286.41 0.0
287.05 0.5
287.61 0.0
288.02 0.3
288.58 0.0
289.11 0.0
289.65 0.0
290.19 0.0
290.72 0.0
291.27 0.0
291.8 0.0

Annotations:

^{0,3}A_{GalNAc}Y ^{1,4}A_{GalNAc} ^{1,4}A_{GlcNAc}
292.36 0.0

Annotations:

^{0,3}A_{GalNAc}Y ^{1,4}A_{GalNAc} ^{1,4}A_{GlcNAc}
292.87 0.0
293.51 0.4
294.05 0.0
294.61 0.0
295.13 0.0
295.69 0.0
296.2 0.0
296.77 0.0
297.28 0.0
297.84 0.0
298.36 0.0
299.12 1.7
299.7 0.0
300.22 0.0
300.71 0.0
301.31 0.0
301.79 0.0
302.39 0.0
303.1 0.4
304.11 4.3
305.16 1.3
305.96 2.1
306.5 0.0
307.09 0.0
307.58 0.0
308.17 0.0
308.67 0.0
309.24 0.0
309.74 0.0
310.27 0.0
311.12 0.7
311.69 0.0
312.21 0.0
312.77 0.0
313.29 0.0
313.73 0.2
314.27 0.0
314.8 0.0
315.36 0.0
315.87 0.0
316.44 0.0
316.95 0.0
317.52 0.0
318.02 0.7
318.57 0.0
319.13 0.2
319.69 0.0
320.21 0.0
320.77 0.0
321.29 0.0
321.85 0.0
322.37 0.0
322.94 0.0
323.52 0.3
324.15 1.1
324.68 0.0
325.17 0.6
325.71 0.0
326.27 0.0
326.79 0.0
327.35 0.0
327.87 0.0
328.21 0.2
329.02 1.0
329.25 0.4
329.68 0.0
330.33 0.0
330.84 0.0
331.42 0.0
331.92 0.0
332.5 0.0
333.0 0.0
333.38 0.0
333.58 0.0
334.08 0.0
335.08 0.2
335.63 0.0
336.19 0.0

Annotations:

^{1,5}A_{GlcNAc}
336.71 0.0
337.27 0.0
337.79 0.0
338.35 0.0
338.87 0.0
339.42 0.0
339.94 0.0
340.69 1.7
341.03 0.5
341.8 0.6
342.36 0.0
343.01 0.5
343.55 0.0
343.96 0.1
344.52 0.0
345.04 0.0
345.6 0.0
347.07 14.9
348.2 1.5
348.92 0.3
349.47 0.0
350.02 0.0
350.54 0.0
351.1 0.0
351.62 0.0
352.28 0.3
352.96 2.1
353.74 0.0
354.22 0.0
354.82 0.0
355.31 0.0
355.9 0.0
356.39 0.0
356.99 0.0
357.46 0.0
358.64 0.3
359.09 1.4
359.65 0.0
360.19 0.0
360.73 0.0
361.26 0.0
361.86 2.4
362.09 1.5
362.66 0.4
363.07 1.2
364.03 46.2

Annotations:

B
365.13 11.4
366.09 12.6

Annotations:

Z
366.62 0.0

Annotations:

Z
367.12 0.3
367.95 0.4
368.49 0.0
369.03 0.0
369.56 0.0
370.11 0.0
371.07 4.7
371.42 1.4
371.95 0.0
372.25 0.0
372.52 0.0
373.03 0.0
373.32 0.0
373.6 0.0
374.11 0.0
374.4 0.0
374.68 0.0
375.19 0.0
375.71 0.0
376.27 0.0
380.47 0.4
380.95 1.0
382.16 0.4

Annotations:

C
382.52 0.0

Annotations:

C
382.89 0.3
383.3 3.2
384.03 13.7

Annotations:

Y
385.07 0.6
385.72 0.8
386.28 0.0
386.8 0.0
387.36 0.0
387.67 0.5
389.0 276.7

Annotations:

ZZ
390.03 46.6
390.96 0.2
391.52 0.0
392.04 0.0
392.6 0.0
393.12 0.0
393.92 0.3
394.47 0.0
395.02 0.0
396.06 2.4
397.04 0.4
397.61 0.0
398.12 0.0
398.69 0.0
399.2 0.0
399.52 0.0
399.77 0.0
400.28 0.0
400.61 0.0
400.85 0.0
401.36 0.0
401.68 0.0
407.02 81.6

Annotations:

ZY YZ
408.13 10.1
408.44 1.9
408.92 0.2
409.47 0.0
410.03 0.0
410.55 0.0
411.11 0.0
411.63 0.0
412.19 0.0
412.7 0.0
413.27 0.0
416.87 0.6
417.44 0.0
417.95 0.0
418.61 0.5
419.14 0.0
419.89 0.4
420.44 0.0
420.96 0.0
421.52 0.0
422.04 0.0
422.6 0.0
423.12 0.0
423.96 25.6

Annotations:

^{0,4}A_{GalNAc}
424.62 0.6

Annotations:

^{0,4}A_{GalNAc}
425.09 4.5

Annotations:

YY
426.12 0.4
426.87 1.0
427.11 0.4
427.69 0.0
428.2 0.0
428.75 0.0
429.28 0.0
429.81 0.0
430.36 0.0
430.89 0.0
431.2 0.7
431.76 0.0
432.28 0.0
432.82 0.0
433.36 0.0
433.89 0.0
434.44 0.0
434.97 0.0
435.52 0.0
436.03 0.0
437.8 0.7

Annotations:

^{3,5}A_{GalNAc}
438.01 0.8

Annotations:

^{3,5}A_{GalNAc}
438.56 0.0

Annotations:

^{3,5}A_{GalNAc}
439.12 0.0
439.64 0.0
440.2 0.0
440.72 0.0
441.25 0.0
441.8 0.0
442.33 0.0
442.87 0.0
448.88 0.5
449.13 0.3
449.82 0.5

Annotations:

^{2,5}A_{GalNAc}Z
450.14 0.7

Annotations:

^{2,5}A_{GalNAc}Z
450.71 0.0
451.27 0.0
451.78 0.0
452.34 0.0
452.86 0.0
453.4 0.0
453.94 0.0

Annotations:

^{0,3}A_{GalNAc}
454.47 0.0

Annotations:

^{0,3}A_{GalNAc}
455.02 0.0
455.9 0.7
456.46 0.0
457.04 0.0
457.53 0.0
458.11 0.0
458.61 0.0
459.15 0.0
459.7 0.0
460.0 0.5
460.54 0.0
461.06 0.2
461.61 0.0
462.26 0.5
462.8 0.0
463.36 0.0
463.87 0.0
464.44 0.0
464.95 0.0
465.52 0.0
465.94 0.4

Annotations:

^{0,2}A_{GalNAc}Z
466.97 1.5
467.49 0.0
468.09 1.4

Annotations:

^{2,5}A_{GalNAc}Y
468.64 0.0

Annotations:

^{2,5}A_{GalNAc}Y
469.19 0.0
469.71 0.0
470.27 0.0
470.79 0.0
471.35 0.0
471.87 0.0
472.43 0.0
472.99 2.9
473.15 2.0
474.03 3.7
474.59 0.0
475.11 0.0
475.66 0.0
476.19 0.0
476.73 0.0
477.27 0.0
477.84 0.3
478.37 0.0
479.06 0.5
479.61 0.0
480.04 1.0
480.61 0.0
481.13 0.0
481.69 0.0
482.21 0.0
482.77 0.0
483.29 0.0
483.85 0.0

Annotations:

^{0,2}A_{GalNAc}Y
484.37 0.0

Annotations:

^{0,2}A_{GalNAc}Y
485.16 1.1
485.7 0.0
486.24 0.3
486.79 0.0
487.35 0.0
487.87 0.0
488.44 0.0
488.95 0.0
489.5 0.0
490.03 0.0
490.56 0.0
491.03 1.7
491.58 0.0
492.21 0.2
492.95 0.2
493.3 0.0
493.52 0.0
494.04 0.0
494.38 0.0
494.6 0.0
495.12 0.0
495.66 0.0
496.2 0.0
496.73 0.0
497.28 0.0
497.79 0.0
505.3 0.6
505.86 0.0
506.37 0.0
507.0 0.2
507.55 0.0
508.11 0.0
509.02 65.6
509.98 6.8
510.2 6.3
510.85 0.0
511.38 0.0
511.93 0.0
512.46 0.0
513.01 0.0
513.54 0.0
514.09 0.0
514.62 0.0
515.13 0.6
515.69 0.0
516.14 1.0
516.69 0.0
517.22 0.0
517.78 0.0
518.3 0.0
518.86 0.0
519.38 0.0
519.94 0.0
521.02 14.7

Annotations:

^{1,5}A_{GalNAc}Z
521.55 0.7

Annotations:

^{1,5}A_{GalNAc}Z
522.23 3.1
522.82 0.0
523.33 0.0
523.9 0.0
524.41 0.0
524.98 0.0
525.49 0.0
526.05 0.0
527.04 171.9
528.18 25.4
529.43 0.0
530.51 0.0
531.59 0.0
533.12 6.5
533.43 0.9
534.06 1.9
534.37 0.8
535.1 0.9
535.64 0.0
536.19 0.0
536.71 0.0
537.27 0.0
537.79 0.0
538.35 0.0
538.87 0.0

Annotations:

^{1,5}A_{GalNAc}Y
539.43 0.0

Annotations:

^{1,5}A_{GalNAc}Y
539.94 0.0
541.01 1.1
541.59 0.0
542.05 0.8
542.61 0.0
543.14 0.0
543.69 0.0
544.22 0.0
545.08 8.7
545.7 0.6
546.14 2.3
546.94 0.0
547.46 0.0
548.02 0.0
548.54 0.0
548.88 1.1
549.44 0.0
549.96 0.0
551.15 7.2
552.13 3.4
552.74 0.0
553.29 0.0
553.82 0.0
554.37 0.0
554.89 0.0
555.44 0.0
555.97 0.0
556.52 0.0
557.05 0.0
566.22 0.3
566.61 0.5
566.99 1.1
567.27 0.5
567.84 0.6
569.04 1750.9

Annotations:

Z Z
570.02 314.0
570.84 0.5
571.37 0.0
571.94 0.0
572.45 0.0
573.02 0.0
573.53 0.0
574.1 0.0
574.61 0.0
575.18 0.0
575.69 0.0
586.27 1.0
587.04 234.6

Annotations:

Y Y
588.15 41.9
588.88 1.7
589.12 1.3
589.35 1.6
589.92 0.0
590.44 0.0
591.0 0.0
591.52 0.0
592.08 0.0
592.6 0.0
593.16 0.0
593.67 0.0
594.22 0.0
598.14 0.3
598.67 0.0
599.2 0.0
599.74 0.0
600.28 0.0
600.81 0.0
601.36 0.0
601.8 0.8
602.36 0.0
602.88 0.0
603.44 0.0
603.96 0.0
604.52 0.0
605.04 0.0
605.6 0.0
606.12 0.0
606.66 0.0
606.99 0.5
607.54 0.0
608.1 0.0
608.61 0.0
609.16 0.0
609.7 0.0
610.23 0.0
610.78 0.0
611.3 0.0
611.85 0.0
614.77 1.1
615.33 0.0
615.86 0.0
616.39 0.0
616.94 0.0
617.47 0.0
618.02 0.0
618.54 0.0
619.11 0.0
619.62 0.0
627.22 0.3
627.77 0.0
628.3 0.0
629.08 2.8
630.09 0.6

Annotations:

^{2,5}A_{GalNAc}
630.45 0.0

Annotations:

^{2,5}A_{GalNAc}
630.68 0.0

Annotations:

^{2,5}A_{GalNAc}
631.34 1.7
631.88 0.0
632.44 0.0
632.96 0.0
633.52 0.0
634.04 0.0
634.6 0.0
635.12 0.0
635.66 0.0
636.33 0.3
636.88 0.0
637.47 0.3
638.02 0.0
638.54 0.0
639.1 0.0
639.62 0.0
640.19 0.0
641.12 0.8
641.45 0.0
641.69 0.0
642.2 0.0
642.53 0.0
642.77 0.0
643.28 0.0
643.61 0.0
643.85 0.0
644.36 0.0
644.71 0.0
644.92 0.0
645.44 0.0
645.96 0.0

Annotations:

^{0,2}A_{GalNAc}
647.44 2.3
647.97 0.6
648.38 0.8
648.81 0.8
649.31 0.3
649.86 0.0
650.39 0.0
650.94 0.0
651.47 0.0
652.02 0.0
652.54 0.0
653.1 0.0
653.62 0.0
654.18 0.0
656.92 0.9
657.49 0.3
658.04 0.0
658.59 0.6
658.83 0.2
659.36 0.0
659.66 0.0
659.93 0.0
660.44 0.0
660.73 0.0
661.01 0.0
661.52 0.0
662.07 0.0
662.6 0.0
663.11 0.0
665.13 0.4
665.69 0.0
666.21 0.0
666.77 0.0
667.29 0.0
667.81 0.3
668.37 0.0
668.93 0.0
669.45 0.0
669.99 0.0
670.53 0.0
671.08 0.4
671.62 0.0
672.04 0.2
672.85 0.9
673.3 0.5
673.87 0.0
674.62 0.6
675.0 0.9
675.31 0.9
675.53 1.9
676.1 0.0
676.61 0.0
677.18 0.0
677.69 0.0
678.24 0.0
678.77 0.0
679.3 0.0
679.86 0.0
680.38 0.0
686.68 0.6
687.23 0.0
687.77 0.0
688.07 0.3
689.1 133.5
690.09 42.3
691.09 0.7
691.9 0.5
692.09 0.4
692.61 0.0
693.18 0.0
693.69 0.0
694.08 0.4
694.86 0.3
695.39 0.0
695.94 0.0
696.47 0.0
697.0 0.4
697.55 0.0
698.11 0.0
698.63 0.0
698.94 0.0
699.19 0.0
699.91 0.7
700.57 0.0
700.99 0.0

Annotations:

^{1,5}A_{GalNAc}
701.66 0.0

Annotations:

^{1,5}A_{GalNAc}
702.07 0.0
702.79 0.4
703.16 0.5
703.71 0.0
704.27 0.0
704.78 0.0
705.35 0.0
705.86 0.0
706.38 1.2
707.06 92.3
708.09 32.1
708.87 0.0
709.39 0.0
709.95 0.0
710.47 0.0
711.02 0.0
711.56 0.0
712.1 0.0
712.78 1.5
713.12 2.2
713.31 1.2
713.85 0.0
714.41 0.0
714.79 0.6
715.33 0.0
715.89 0.0
716.41 0.0
716.97 0.0
717.49 0.0
718.05 0.0
718.57 0.0
719.12 0.0
719.64 0.0
720.52 2.0
721.1 0.0
721.61 0.0
722.16 0.0
722.7 0.0
723.23 0.0
723.78 0.0
724.3 0.0
724.86 0.0
725.38 0.0

There are 11 similar spectra:

Id Structure Score

3118

1.00

3754

0.99

4237

0.99

5229

0.99

4081

0.98

4805

0.97

3119

0.84

4849

0.83

5230

0.73

4238

0.73

5201

0.61
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